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Antigenic Specificity | TTF-1 |
Clone | 8G7G3/1 |
Host Species | Mouse |
Reactive Species | human, rat |
Isotype | IgG1 |
Format | purified |
Size | 6 mL |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-TTF-1. Transcription termination factor-1 (TTF-1) plays a critical role in ribosomal gene transcription. This transcription factor mediates the termination of RNA polymerase I transcription by binding to Sal box terminator elements downstream of pre-rRNA coding regions. It binds to and activates the promoter of thyroid specific genes such as thyroglobulin, thyrotropin receptor, and thyroperoxidase. TTF-1 is important in the maintenance of the thyroid differentiation phenotype. |
Immunogen | This antibody was developed using a rat TTF-1 recombinant protein. |
Other Names | Thyroid Transcription Factor, Homeobox protein Nkx-2.1, thyroid nuclear factor 1, thyroid transcription factor 1 TTF-1 NK-2 |
Gene, Accession # | Gene ID: 25628 |
Catalog # | 918101 |
Price | $307 |
Order / More Info | TTF-1 Antibody from BIOLEGEND |
Product Specific References | n/a |