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Antigenic Specificity | P62 (SQSTM1) |
Clone | 1B5.H9 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1, κ |
Format | purified, azide-free |
Size | 100 µL |
Concentration | n/a |
Applications | IHC-P, Western Blot (WB), ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified (azide-free) anti-p62 (SQSTM1). The p62 protein, also called sequestosome 1 (SQSTM1), is a ubiquitin-binding scaffold protein that colocalizes with ubiquitinated protein aggregates in many neurodegenerative diseases and proteinopathies of the liver. The protein is able to polymerize via an N-terminal PB1 domain and can interact with ubiquitinated proteins via the C-terminal UBA domain. Also, p62/SQSTM1 binds directly to LC3 and GABARAP family proteins via a specific sequence motif. The protein is itself degraded by autophagy a |
Immunogen | This monoclonal antibody was raised against a peptide sequence corresponding to amino acids 201-212 of the human SQSTM 1 (isoform 1) protein conjugated to KLH. |
Other Names | P60, p62, A170, OSIL, PDB3, ZIP3, p62B, sequestosome-1, oxidative stress-induced-like ubiquitin-binding protein p62 |
Gene, Accession # | Gene ID: 8878 |
Catalog # | 814801 |
Price | $275 |
Order / More Info | P62 (SQSTM1) Antibody from BIOLEGEND |
Product Specific References | PubMed: 30760704, 31831743 |