Edit |   |
---|---|
Antigenic Specificity | IGBP-1 |
Clone | 5F6 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1, κ |
Format | purified, azide-free |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blot (WB), ICC, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified (azide-free) anti-IGBP-1. IGBP1 (also known as Alpha4) , binds to PP2A C in the absense of A and a B subunit in a catalytically inactive state to prevent C proteosomal degradation. If alpha4 levels are low, PP2A levels can decrease, leading to increased tau protein phosphorylation and aggregation. Protein phosphatase 2A is a heterotrimeric protein serine/threonine phosphatase consisting of a 36-kD catalytic C subunit (alpha and beta isoforms), a 65-kD structural A subunit (alpha and beta isoforms), and a variable regula |
Immunogen | This monoclonal antibody was raised against an N-terminal 6-HIS tagged fusion protein corresponding to full-length mouse Alpha4 protein. |
Other Names | Alpha4, Immunoglobulin-binding protein 1, CD79a-binding protein 1, phosphoprotein, component, 52 kD, lymphocyte signal transduction molecule alpha 4, ALPHA-4, IBP1, renal carcinoma antigen NY-REN-16 |
Gene, Accession # | Gene ID: 8518 |
Catalog # | 828601 |
Price | $275 |
Order / More Info | IGBP-1 Antibody from BIOLEGEND |
Product Specific References | n/a |