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Antigenic Specificity | Mouse CD366 (Tim-3) |
Clone | QA20A20 |
Host Species | Recombinant Mouse |
Reactive Species | mouse |
Isotype | IgG1, κ |
Format | phycoerythrin (PE) conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PE anti-mouse CD366 (Tim-3) Recombinant. CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on Th1 lymphocytes and CD11b+ macrophages. Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance. |
Immunogen | n/a |
Other Names | CD366, Tim-3, Hepatitis A virus cellular receptor 2 homolog (HAVcr-2) |
Gene, Accession # | Gene ID: 171285 |
Catalog # | 165404 |
Price | $255 |
Order / More Info | Mouse CD366 (Tim-3) Antibody from BIOLEGEND |
Product Specific References | n/a |