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Antigenic Specificity | P62 (SQSTM1) |
Clone | O95A2 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-p62 (SQSTM1). In eukaryotes, autophagy plays a critical role in the maintenance of cellular proteostasis. Sequestosome-1 (SQSTM1), or p62 functions as a receptor during selective macroautophagy, where it is responsible for recognition and loading of misfolded proteins and dysfunctional organelles into autophagosomes for cytosolic clearance and recycling. p62 contains a ubiquitin-association (UBA) domain which directly binds ubiquitinated protein aggregate substrates. Under normal conditions, p62 exists as a d |
Immunogen | Full-length recombinant human SQSTM1 protein |
Other Names | Sequestosome 1, p62, Phosphotyrosine-Independent Ligand For The Lck SH2 Domain Of 62 KDa, EBI3-Associated Protein Of 60 KDa, Ubiquitin-Binding Protein p62, Oxidative Stress Induced Like, Autophagy Receptor P62 |
Gene, Accession # | Gene ID: 8878 |
Catalog # | 937202 |
Price | $253 |
Order / More Info | P62 (SQSTM1) Antibody from BIOLEGEND |
Product Specific References | n/a |