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Antigenic Specificity | Human CD86 |
Clone | IT2.2 |
Host Species | Mouse |
Reactive Species | human, cynomolgus, rhesus |
Isotype | IgG2b, kappa |
Format | PE-Fire™ 700 conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | FC - Quality tested |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PE/Fire™ 700 anti-human CD86. CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells. |
Immunogen | n/a |
Other Names | B7-2, B70 |
Gene, Accession # | Gene ID: 942 |
Catalog # | 305464 |
Price | $382 |
Order / More Info | Human CD86 Antibody from BIOLEGEND |
Product Specific References | n/a |