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Antigenic Specificity | Presenilin 1 (NH2 terminus) |
Clone | NT1 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified, azide-free |
Size | 200 µL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified (azide-free) anti-Presenilin 1 (NH2 terminus). Presenilin 1 is one of two transmembrane related-proteins, the other being Presenilin 2, that form the catalytic subunits of the gamma-secretase intramembrane protease complex. The gamma secretase complex catalyzes cleavage of a number of integral membrane proteins including Amyloid precursor protein (APP), Notch, Erb4 and E-cadherin. |
Immunogen | BioLegend?s mouse anti-Presenilin 1 was raised against a portion of the n-terminal region of Presenilin 1 (RRSLGHPEP). |
Other Names | AD3, FAD, PS-1, S182, presenilin-1, gamma-secretase |
Gene, Accession # | Gene ID: 5663 |
Catalog # | 823401 |
Price | $501 |
Order / More Info | Presenilin 1 (NH2 terminus) Antibody from BIOLEGEND |
Product Specific References | PubMed: 23575824 |