ApoER2 (LRP8) Antibody from BIOLEGEND
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| Antigenic Specificity | ApoER2 (LRP8) |
| Clone | 25G5 |
| Host Species | Rat |
| Reactive Species | human, mouse, rat |
| Isotype | IgG2a, κ |
| Format | purified |
| Size | 100 µg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Purified anti-ApoER2 (LRP8). LDL Receptor Related Protein 8 (LRP8), also known as ApoER2, is a receptor for members of low-density lipoproteins. LRP8 interacts with its ligand reelin, and triggers reelin signaling to regulate cellular processes such as neuronal cell migration and long-term potentiation of mature neurons. LRP8 also interacts with and downregulates APP endocytosis. This interactions leads to increased amyloid beta production, demonstrating a major role for LRP8 in the pathogenesis of Alzheimer's disease. |
| Immunogen | n/a |
| Other Names | LRP8, APOER2, LDL Receptor Related Protein 8 |
| Gene, Accession # | Gene ID: 7804, 16975 |
| Catalog # | 862102 |
| Price | $276 |
| Order / More Info | ApoER2 (LRP8) Antibody from BIOLEGEND |
| Product Specific References | n/a |
BIOLEGEND
BIOLEGEND
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http://www.biolegend.com
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