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Antigenic Specificity | CD28 |
Clone | 204.12 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG2a, kappa |
Format | Protein G purified |
Size | 100 ug, 20 ug |
Concentration | n/a |
Applications | FACS, IF |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes a glycoprotein of 44-88kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader. |
Immunogen | Stimulated human leukocytes were used as the immunogen for the CD28 antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P10747 |
Catalog # | orb749882 |
Price | $764 |
Order / More Info | CD28 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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