SUR2A Antibody from BIORBYT LTD.
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| Antigenic Specificity | SUR2A |
| Clone | S319A-14 |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG2A |
| Format | peroxidase (HRP) conjugate |
| Size | 100 ug |
| Concentration | 1 mg/ml |
| Applications | ICC, IHC, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Mouse monoclonal to SUR2A (HRP). Sulfonylurea receptors (SUR) are membrane proteins which are the molecular targets of the sulfonylurea class of anti-diabetic drugs whose mechanism of action is to promote insulin release from pancreatic beta cells. More specifically, SUR proteins are subunits of the inward-rectifier potassium ion channels Kir6. x (6. 1 and 6. 2). The association of four K ir6. x and four SUR subunits form an ion conducting channel commonly referred to as the K ATP channel. The primary function of the sulfonylurea receptor is to sense intracellular levels of the nucleotides ATP and ADP and in response facilitate the open or closing its associated Kir 6. x potassium channel. Hence the K ATP channel monitors the energy balance within the cell.. |
| Immunogen | Fusion protein amino acids 1505-1546 (SSIVDAGLVLVFSEGILVECDTGPNLLQHKNGLFSTLVMTNK, cytoplasmic C-terminus) of mouse SUR2A |
| Other Names | ABCC9, Sulfonylurea receptor 2, CMD10, ABC37, ATP-binding cassette transporter sub-family C member 9, Sulfonylurea receptor 2A, isoform SUR2A |
| Gene, Accession # | Gene ID: 20928, UniProt: P70170 |
| Catalog # | orb150356 |
| Price | $556 |
| Order / More Info | SUR2A Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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