LXR alpha Antibody from BIORBYT LTD.

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Antigenic SpecificityLXR alpha
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman, rat
IsotypeIgG
Formatunconjugated
Size100 ul
Concentration1mg/ml
ApplicationsIHC, WB
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DescriptionOrphan receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.
ImmunogenA synthetic peptide of human LXR alpha
Other NamesNR1H3; LXRA; Oxysterols receptor LXR-alpha; Liver X receptor alpha; Nuclear receptor subfamily 1 group H member 3
Gene, Accession #Gene ID: 10062, UniProt: Q13133
Catalog #orb1731735
Price$345
Order / More InfoLXR alpha Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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Email: info@biorbyt.com
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