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Antigenic Specificity | LXR alpha |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | IgG |
Format | unconjugated |
Size | 100 ul |
Concentration | 1mg/ml |
Applications | IHC, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Orphan receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8. |
Immunogen | A synthetic peptide of human LXR alpha |
Other Names | NR1H3; LXRA; Oxysterols receptor LXR-alpha; Liver X receptor alpha; Nuclear receptor subfamily 1 group H member 3 |
Gene, Accession # | Gene ID: 10062, UniProt: Q13133 |
Catalog # | orb1731735 |
Price | $345 |
Order / More Info | LXR alpha Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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