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Antigenic Specificity | KDM7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 100 ul |
Concentration | n/a |
Applications | IP, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal to KDM7.Lysine-specific histone demethylase 7 (KDM7) is a histone demethylase required for braindevelopment. KDM7 specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 andH3K27me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue(H4K20Me1), thereby playing a central role in histone code. KDM7 specifically binds trimethylated'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3,it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. |
Immunogen | C-terminal region of human KDM7 |
Other Names | KDM7 |
Gene, Accession # | UniProt: Q6ZMT4 |
Catalog # | orb67004 |
Price | $462 |
Order / More Info | KDM7 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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