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Antigenic Specificity | APC |
Clone | FAD-1 |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | IgG |
Format | unconjugated |
Size | 100 ul, 100 ul, 100 ul, 30 ul |
Concentration | Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
Applications | ICC, IF, IHC, IP, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | APC Monoclonal Antibody |
Immunogen | A synthesized peptide derived from human APC Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF) -induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. |
Other Names | n/a |
Gene, Accession # | UniProt: P25054 |
Catalog # | orb546977 |
Price | $520 |
Order / More Info | APC Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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