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Antigenic Specificity | Calbindin / CALB1 |
Clone | rCALB1/8499 |
Host Species | Recombinant Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | unconjugated |
Size | 20 ug |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The family of EF-hand type Ca2+-binding proteins includes Calbindin D28K, Calbindin D9K, S-100 Alpha and Beta, Calgranulin A (also designated MRP8), Calgranulin B (also designated MRP14), Calgranulin C and the Parvalbumin family members, including Parvalbumin Alpha and Parvalbumin Beta (also designated oncomodulin). Calbindin D28K, also known as calbindin, CALB1, D-28K or vitamin D-dependent calcium-binding protein, is a 261-amino acid protein with 6 EF-hand domains, 4 of which are active calcium-binding domains. Expressed in brain, ovary, uterus, testis, pancreas, liver, kidney and intestine, Calbindin D28K acts as a calcium-buffering agent and alters the activity of the plasma membrane ATPase. In neuronal cells, Calbindin D28K modulates calcium channel activity, calcium transients and intrinsic neuronal firing activity. Also, Calbindin D28K has been implicated to play a role in apoptosis and microtubule function. |
Immunogen | A recombinant partial protein sequence (within amino acids 7-96) from the human protein was used as the immunogen for the CALB1 antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P05937 |
Catalog # | orb1822851 |
Price | $405 |
Order / More Info | Calbindin / CALB1 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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