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Antigenic Specificity | LXRA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 100 ul |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal to LXRA.Liver X receptor alpha (LXRA) belongs to the nuclear hormone receptor family, NR1 subfamily. LXRAis an orphan receptor. LXRA can form a heterodimer with RXR, which shifts RXR from a silent DNAbindingpartner to an active ligand-binding subunit in mediating retinoid responses through targetgenes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats oftwo similar hexanuclotide half-sites spaced by four nucleotides. LXRA plays an important role in theregulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependentubiquitination of LDLR, VLDLR and LRP8. |
Immunogen | middle region of human LXRA |
Other Names | LXRA,Oxysterols receptor LXRalpha,Liver X receptor alpha,Nuclear receptor subfamily 1 group H member3,NR1H3 |
Gene, Accession # | UniProt: Q13133 |
Catalog # | orb67061 |
Price | $527 |
Order / More Info | LXRA Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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