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Antigenic Specificity | AKT1 |
Clone | AKT1/2784 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG |
Format | Protein G purified |
Size | 100 ug, 20 ug |
Concentration | n/a |
Applications | IHC-P, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes a protein of 62kDa, which is identified as AKT1. The serine/threonine kinase Akt family contains several members, including Akt1 (also designated PKB or RacPK), Akt2 (also designated PKB tyrosine residues 740 and 751, which bind the subunit of the phosphatidylinositol 3-kinase (PI 3-kinase) complex. Activation of Akt1 by insulin or insulin-growth factor-1 (IGF-1) results in phosphorylation of both Thr 308 and Ser 473. Akt proteins become phosphorylated and activated in insulin/IGF-1-stimulated cells by an upstream kinase(s), and the activation of Akt1 and Akt2 is inhibited by the PI kinase inhibitor wortmannin. |
Immunogen | Amino acids 85-189 from the human protein were used as the immunogen for the AKT1 antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P31749 |
Catalog # | orb639633 |
Price | $764 |
Order / More Info | AKT1 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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