Edit |   |
---|---|
Antigenic Specificity | Podocalyxin / PODXL |
Clone | 4F10 |
Host Species | Mouse |
Reactive Species | human, rat |
Isotype | IgM, kappa |
Format | PEG purified |
Size | 100 ug, 20 ug |
Concentration | n/a |
Applications | FACS, IF, IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Podocalyxin/PODXL is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology. |
Immunogen | A recombinant protein fragment containing the intracellular, transmembrane, and part of the extracellular domain of human Podocalyxin was used as the immunogen for the PODXL antibody. |
Other Names | n/a |
Gene, Accession # | Gene ID: 5420, UniProt: O00592 |
Catalog # | orb749746 |
Price | $764 |
Order / More Info | Podocalyxin / PODXL Antibody from BIORBYT LTD. |
Product Specific References | n/a |
U.S. OFFICE
Biorbyt LLC
1100 Corporate Square Drive
Helix Center, Suite 221
St Louis, MO 63132
Email: info@biorbyt.com
Phone: +1 (415) 906-5211
Fax: +1 (415) 651-8558