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Antigenic Specificity | Estrogen Receptor alpha |
Clone | rESR1/8761 |
Host Species | Recombinant Mouse |
Reactive Species | human |
Isotype | IgG2b, kappa |
Format | unconjugated |
Size | 100 ug |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes a protein of 67kDa, which is identified as estrogen receptor (ER) alpha. The ER gene consists of more than 140kb of genomic DNA divided into 8 exons, being translated into a protein with six functionally discrete domains, labeled A through F. This antibody strongly stains the nucleus of epithelial cells in breast carcinomas.The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to antiestrogen (e.g. tamoxifen) therapy. |
Immunogen | A recombinant fragment corresponding to the C-terminus of human ER-alpha was used as the immunogen for the Estrogen Receptor alpha antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P03372 |
Catalog # | orb1823110 |
Price | $764 |
Order / More Info | Estrogen Receptor alpha Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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