MYLIP Antibody from BIORBYT LTD.
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|---|---|
| Antigenic Specificity | MYLIP |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 100 ul |
| Concentration | n/a |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal to MYLIP.Myosin regulatory light chain interacting protein (MYLIP) is also known as inducible degrader of theLDL-receptor (IDOL), which is an E3 ubiquitin-protein ligase that mediates ubiquitination andsubsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR andLRP8. Proteasomal degradation of MRLC leads to the inhibition of neurite outgrowth in the presenceof NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) andreducing CNPY2-stimulated neurite outgrowth. MYLIP also acts as a sterol-dependent inhibitor ofcellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR. |
| Immunogen | C-terminal region of human MYLIP |
| Other Names | MYLIP,E3 ubiquitinprotein ligase MYLIP,Inducible degrader of the LDLreceptor,Idol,IDOL,Myosinregulatory light chain interacting protein,MIR,BZF1,BM023,PP5242 |
| Gene, Accession # | UniProt: Q8WY64 |
| Catalog # | orb66979 |
| Price | $527 |
| Order / More Info | MYLIP Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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