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Antigenic Specificity | p300 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 100 ul |
Concentration | n/a |
Applications | ELISA, ICC, IHC, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | EP300: E1A binding protein p300. This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. |
Immunogen | Synthesized peptide derived from the Internal region of human p300. |
Other Names | EP300; P300; Histone acetyltransferase p300; p300 HAT; E1A-associated protein p300 |
Gene, Accession # | Gene ID: 2033, UniProt: Q09472 |
Catalog # | orb1729714 |
Price | $296 |
Order / More Info | p300 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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