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Antigenic Specificity | PD-L1 / B7-H1 / CD274 |
Clone | PDL1/8408R |
Host Species | Recombinant Rabbit |
Reactive Species | human |
Isotype | IgG, kappa |
Format | unconjugated |
Size | 20 ug |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system. |
Immunogen | A recombinant partial protein sequence (within amino acids 190-290) from the human protein was used as the immunogen for the PD-L1 antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: Q9NZQ7 |
Catalog # | orb1822761 |
Price | $405 |
Order / More Info | PD-L1 / B7-H1 / CD274 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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