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Antigenic Specificity | ACE / Angiotensin I Converting Enzyme |
Clone | ACE/3762 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2c, kappa |
Format | Protein G purified |
Size | 20 ug, 100 ug |
Concentration | n/a |
Applications | ELISA, IHC-P, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined. |
Immunogen | A portion of amino acids 652-788 from the human protein was used as the immunogen for the ACE antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P12821 |
Catalog # | orb699591 |
Price | $405 |
Order / More Info | ACE / Angiotensin I Converting Enzyme Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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