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Antigenic Specificity | CD303 |
Clone | monoclonal |
Host Species | n/a |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | unconjugated |
Size | 0.1 mg |
Concentration | 1 mg/ml |
Applications | ELISA, FC, ICC, IHC-Fr |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD303 is an approximately 38 kDa type II transmembrane glycoprotein with an extracellular C-type lectin domain. It is a specific marker of plasmacytoid dendritic cells, and plays roles in capturing of pathogen-related oligosaccharide-containing antigens by them, and in their presentation to T cells. CD303 also mediates a potent inhibition of interferon alpha/beta production in plasmacytoid dendritic cells, thus it represents a potential target for lupus erythematosus therapy. |
Immunogen | CD303 ectodomain fused with human IgG Fc domain |
Other Names | BDCA2, CLEC4C, DLEC, HECL, CLECSF7, CLECSF11, PRO34150 |
Gene, Accession # | Gene ID: 170482, UniProt: Q8WTT0 |
Catalog # | orb1742787 |
Price | $304 |
Order / More Info | CD303 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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