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Antigenic Specificity | ZNF488 |
Clone | PCRP-ZNF488-2D8 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | unconjugated |
Size | 100 ug |
Concentration | n/a |
Applications | FACS, IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Zinc finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc finger proteins contain a Kruppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF488 is a 340 amino acid transcriptional regulator belonging to the Kruppel C2H2-type zinc finger protein family. ZNF488 localizes to the nucleus and contains two C2H2-type zinc fingers. ZNF488 is encoded by a gene located on chromosome 10, which contains a plethora of interesting genes and represents between 4 and 4.5 percent of the total DNA in cells. Jackson-Weiss, Cowden and Usher syndromes are a few diseases related to genes on chromosome 10. |
Immunogen | A recombinant partial protein (within amino acids 170-307) from the human protein was used as the immunogen for the ZNF488 antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: Q96MN9 |
Catalog # | orb1826276 |
Price | $764 |
Order / More Info | ZNF488 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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