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Antigenic Specificity | CD11b / MAC-1 |
Clone | M1/70 |
Host Species | Rat |
Reactive Species | human, mouse |
Isotype | IgG2b, kappa |
Format | Protein G purified |
Size | 100 ug, 20 ug |
Concentration | n/a |
Applications | FACS, Functional Studies, IF |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD11b is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin alpha-M (CD11b) combines with the Integrin beta-2 (CD18) to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin alpha-M/beta-2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. |
Immunogen | B10 mouse spleen cells enriched for T lymphocytes were used as the immunogen for this CD11b antibody. |
Other Names | n/a |
Gene, Accession # | Gene ID: 3684 |
Catalog # | orb248418 |
Price | $764 |
Order / More Info | CD11b / MAC-1 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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