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Antigenic Specificity | CD272 |
Clone | MIH26 |
Host Species | Mouse |
Reactive Species | human, primate |
Isotype | IgG2a kappa |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | 1 mg/ml |
Applications | FC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD272, a type I transmembrane glycoprotein, contains in its intracellular domain two ITIM sequences, which are upon CD272 triggering phosphorylated and recruit SHP phosphatases to attenuate cell activation. CD272 is expressed on B and T lymphocytes, NK cells, dendritic cells, and macrophages, and its ligand is CD270. Defects in CD272-CD270 inhibitory mechanism lead to autoimmune diseases. Overexpression of CD272 is a marker of tolerant T cells. |
Immunogen | cells transfected with human CD272 |
Other Names | BTLA1 |
Gene, Accession # | Gene ID: 151888, UniProt: Q7Z6A9 |
Catalog # | orb1088502 |
Price | $304 |
Order / More Info | CD272 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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