Edit |   |
---|---|
Antigenic Specificity | MLL2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 100 ul |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal to MLL2.MLL2 is a histone methyltransferase that methylates 'Lys-4' of histone H3 (H3K4me). H3K4merepresents a specific tag for epigenetic transcriptional activation. MLL2 plays a central role in betaglobinlocus transcription regulation by being recruited by NFE2. MLLS acts as a coactivator forestrogen receptor by being recruited by ESR1, thereby activating transcription. MLL2 is also requiredduring the transcriptionally active period of oocyte growth for the establishment and/or maintenance ofbulk H3K4 trimethylation (H3K4me3), global transcriptional silencing that preceeds resumption ofmeiosis, oocyte survival and normal zygotic genome activation. |
Immunogen | N-terminal region of human MLL2 |
Other Names | MLL2,Histonelysine Nmethyltransferase MLL2,ALL1related protein,ALR,KMT2B,Lysine Nmethyltransferase2B,Myeloid,lymphoid or mixedlineage leukemia protein 2 |
Gene, Accession # | UniProt: O14686 |
Catalog # | orb66850 |
Price | $527 |
Order / More Info | MLL2 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
U.S. OFFICE
Biorbyt LLC
1100 Corporate Square Drive
Helix Center, Suite 221
St Louis, MO 63132
Email: info@biorbyt.com
Phone: +1 (415) 906-5211
Fax: +1 (415) 651-8558