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Antigenic Specificity | HDAC3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 100 ul |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | HDAC3 is a nuclear and cytoplasmic protein that deacetylates both histone (H2A, H3, H4) and non-histone substrates (RelA, SRY, p53, MEF2, PCAF and p300/CBP). HDAC3 deacetylase activity is stimulated by interactions with the N-CoR and SMRT co-repressor proteins. Together, these three proteins form a functional complex that represses transcription associated with nuclear hormone receptors and other transcription factors, including Rev-Erb, COUP-TF, DAX1, MAD and Pit-1. |
Immunogen | Peptide sequence around aa.420~424(N-D-K-E-S) derived from Human HDAC3. |
Other Names | HDAC3; Histone deacetylase 3; HD3; RPD3-2; SMAP45 |
Gene, Accession # | Gene ID: 8841, UniProt: O15379 |
Catalog # | orb1729744 |
Price | $296 |
Order / More Info | HDAC3 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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