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Antigenic Specificity | CD123 |
Clone | 6H6 |
Host Species | n/a |
Reactive Species | human |
Isotype | IgG1 |
Format | PerCP conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | FC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD123 is the alpha chain of interleukin 3 receptor (IL-3R alpha). This subunit heterodimerizes with the interleukin 3 receptor beta chain (CD131), which is shared with other receptors. CD123 interacts with IL-3 specifically, but with low affinity, and association with the beta subunit confers high affinity binding to the receptor heterodimer. Both chains are required for signaling, but receptor activation and signal transduction depend on IL-3 binding to CD123 as the initial step. |
Immunogen | IL3 receptor alpha chain expressed on the surface of transiently transfected COS cells |
Other Names | IL3RA, MGC34174, hIL-3Ra |
Gene, Accession # | Gene ID: 3563, UniProt: P26951 |
Catalog # | orb1742779 |
Price | $439 |
Order / More Info | CD123 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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