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Antigenic Specificity | ICAM-3 |
Clone | JA4 |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1/k |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA, FC, ICC, IHC-Fr, IP, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse monoclonal to ICAM-3. Intercellular adhesion molecule 3 (ICAM3) also known as CD50 (Cluster of Differentiation 50), is a type I transmembrane glycoprotein, which normally contain 2-9 immunoglobulin-like C2-type domains, and binds to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. ICAM-3 has previously been implicated in apoptotic cell clearance, although its precise role in the clearance process is ill defined. |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | UniProt: P32942 |
Catalog # | orb137662 |
Price | $448 |
Order / More Info | ICAM-3 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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