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Antigenic Specificity | CD63 / LAMP-3 |
Clone | CDLA63-2R |
Host Species | Recombinant Rabbit |
Reactive Species | human |
Isotype | IgG, kappa |
Format | Protein A purified |
Size | 100 ug, 20 ug |
Concentration | n/a |
Applications | FACS, IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD63 functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli. [UniProt] |
Immunogen | Full-length recombinant human protein was used as the immunogen for the recombinant CD63 antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P08962 |
Catalog # | orb534409 |
Price | $764 |
Order / More Info | CD63 / LAMP-3 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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