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Antigenic Specificity | Phospho-4E BP1 (Thr70) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 100 ul |
Concentration | n/a |
Applications | IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Translation repressor protein 4E-BP1 (also known as PHAS-1) inhibits cap-dependent translation by binding to the translation initiation factor eIF4E. Hyperphosphorylation of 4E-BP1 disrupts this interaction and results in activation of cap-dependent translation. Both the PI3 kinase/Akt pathway and FRAP/mTOR kinase regulate 4E-BP1 activity. |
Immunogen | Synthetic peptide of human EIF4EBP1 |
Other Names | EIF4EBP1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I |
Gene, Accession # | Gene ID: 1978, UniProt: Q13541 |
Catalog # | orb1730626 |
Price | $296 |
Order / More Info | Phospho-4E BP1 (Thr70) Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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