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Antigenic Specificity | HCV-N-G5 protein |
Clone | monoclonal |
Host Species | Recombinant |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 100 ug |
Concentration | n/a |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | HCV-N-G5 (residues 2-119) protein.The protein contains the HCV core nucleocapsid immunodominant regions, amino acids: 1-102.Hepatitis C Virus core proteins are purified by proprietarychromatographic techniques.The hepatitis C virus (HCV) core protein represents thefirst 191 amino acids of the viral precursor polyproteinand is cotranslationally inserted into the membrane of theendoplasmic reticulum (ER)Hepatitis C virus (HCV) core is a viral structural protein;it also participates in some cellular processes, includingtranscriptional regulation. However, the mechanisms ofcore-mediated transcriptional regulation remain poorlyunderstood. Hepatitis C virus (HCV) core protein isthought to contribute to HCV pathogenesis through itsinteraction with various signal transduction pathwaysIn addition, HCV core antigen is a recently developedmarker of hepatitis C infection. It is remarkably efficientat establishing persistent infection, suggesting that ithas evolved one or more strategies aimed at evadingthe host immune response. T cell responses, includinginterferon-gamma production, are severely suppressedin chronic HCV patients. The HCV core protein hasbeen previously shown to circulate in the bloodstream ofHCV-infected patients and inhibit host immunity throughan interaction with gC1qR. |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | orb97895 |
Price | $616 |
Order / More Info | HCV-N-G5 protein Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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