Phosphotyrosine Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-Phosphotyrosine antibody, protein, ELISA kits.
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| Antigenic Specificity | Phosphotyrosine |
| Clone | G104 |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG1 |
| Format | alkaline phosphatase (AP) conjugate |
| Size | 100 ug |
| Concentration | 1 mg/ml |
| Applications | ICC, IHC, IP, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Mouse monoclonal to Phosphotyrosine (Alkaline Phosphatase). Protein phosphorylation is an important posttranslational modification that serves many key functions to regulate a proteins activity, localization, and protein-protein interactions. Phosphorylation is catalyzed by various specific protein kinases, which involves removing a phosphate group from ATP and covalently attaching it to to a recipient protein that acts as a substrate. Most kinases act on both serine and threonine; others act on tyrosine, and a number (dual specificity kinases) act on all three. Because phosphorylation can occur at multiple sites on any given protein, it can therefore change the function or localization of that protein at any time. Changing the function of these proteins has been linked to a number of diseases, including cancer, diabetes, heart disease, inflammation and neurological disorders (4-6). In particular, the phosphorylation of tyrosine is considered one of the key steps in signal transduction and regulation of enzymatic activity. Phosphotyrosine can be detected through specific antibodies, and are helpful in facilitating the identification of tyrosine kinase substrates.. |
| Immunogen | Phosphotyrosine, alanine and glyceine in a 1:1:1 ratio polymerized in the presence of keyhole limpet hemocyanin with 1-ethyl-3-(3'-dimentrylaminopropyl) carbodiimide |
| Other Names | PhosphoTyrosine (pY), PhosphoTyrosine (pY) |
| Gene, Accession # | n/a |
| Catalog # | orb147702 |
| Price | $546 |
| Order / More Info | Phosphotyrosine Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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