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Antigenic Specificity | PARP (Cleaved) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2bκ |
Format | unconjugated |
Size | 1 ea |
Concentration | n/a |
Applications | Flow Cytometry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Antigen: synthetic peptide containing amino acids near the 214/215 cleavage site of human PARP • Isotype: IgG2bκ • Host: mouse • Cross Reactivity: (+) human PARP • Application(s): FC (intracellular) and WB • PARP is a 116 kDa nuclear chromatin-associated enzyme that is cleaved during apoptosis by caspase-3 into a 24 kDa fragment containing the DNA binding domain and an 89 kDa fragment containing the catalytic and automodification domains. The 24 kDa fragment irreversibly binds to DNA and may contribute to the irreversibility of apoptosis by blocking the access of DNA repair enzymes to DNA strand breaks. |
Immunogen | synthetic peptide containing amino acids near the 214/215 cleavage site of human PARP |
Other Names | poly ADP ribose polymerase ADP-ribose DNA western blots immunoblotting WB flow cytometry intracellular antibodies FC blotting |
Gene, Accession # | n/a |
Catalog # | 13557-1 |
Price | $359.00 |
Order / More Info | PARP (Cleaved) Antibody from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |