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Antigenic Specificity | BDP1 (immunotoxin) |
Clone | monoclonal |
Host Species | Human |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | Cytotoxicity assay, Function study, |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | transferrin-PAP immunotoxin. This immunotoxin was achieved by conjugating/fusing the transferrin to Pokeweed antiviral protein. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to tumor cells and the toxin enters cells by receptor-mediated endocytosis. Then PAP is introduced into the cytoplasm where it eventually causes cell death by inactivating ribosomes. It was designed for treatment of myelogenous leukemia. |
Immunogen | n/a |
Other Names | BDP1; B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB; TFC5; TFNR; TAF3B1; TFIIIB; TFIIIB90; HSA238520; TFIIIB150; transcription factor TFIIIB component B homolog; transcription factor IIIB 150; transcription factor-like nuclear regulator; RNA polymerase III transcription initiation factor B; TATA box binding protein (TBP)-associated factor, RNA polymerase III, GTF3B subunit 1; Pokeweed Antiviral Protein; Pokeweed; PAP |
Gene, Accession # | UniProt: A6H8Y1 |
Catalog # | AGTO-G074P |
Price | please inquire |
Order / More Info | BDP1 (immunotoxin) Antibody from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |