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Antigenic Specificity | DENV-1 |
Clone | monoclonal |
Host Species | Recombinant Human |
Reactive Species | DENV |
Isotype | n/a |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | ELISA, FACS, |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recombinant Human Anti-DENV-1 Antibody (HMAb 1F4 ). Recombinant Human Antibody (HMAb 1F4 ) is capable of binding to DENV-1, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-DENV-1 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-DENV-1 proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. HMAb 1F4, a DENV1-specific Abs, can neutralize DENV at different stages of viral entry in a cell type and receptor dependent manner. HMAb 1F4 binds to the DI and DI-II hinge regions of the E protein monomer and that Ab binding is likely to be sensitive to the hinge angle between DI-II. |
Immunogen | Dengue virus 1 |
Other Names | Dengue virus; DENV; Flaviviridae; dengue virus 1; DENV 1; Flaviviridae |
Gene, Accession # | n/a |
Catalog # | PABL-443 |
Price | please inquire |
Order / More Info | DENV-1 Antibody from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |