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Antigenic Specificity | huntingtin (specific for expanded polyQ by western blot) |
Clone | MW1 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b, kappa |
Format | supernatant |
Size | 1 ml |
Concentration | n/a |
Applications | ELISA,FACS,Function Blocking,Immunofluorescence,Immunoprecipitation,Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Epitope: N-terminal, polyQ. MW1 is specific for the elongated polyQ stretch through which mHtt aggregates. The epitope is hidden in aggregates. This antibody is also known as anti-polyQ. Appears to recognize an altered conformation of the polyQ domain generated as the polyQ domain of Htt increases in length. Time-resolved Foerster resonance energy transfer (TR-FRET) assay has been developed using MW1 to assay soluble huntingtin. PMID: 22365609 23966247 23626768 23100324 22984513. RRID:AB_528290 |
Immunogen | Recombinant DRPLA-19Q/GST fusion protein, Partial protein |
Other Names | HD, IT15 |
Gene, Accession # | HTT, Gene ID: 3064, UniProt: P42858 |
Catalog # | MW1 |
Price | please inquire |
Order / More Info | huntingtin (specific for expanded polyQ by western blot) Antibody from DEVELOPMENTAL STUDIES HYBRIDOMA BANK |
Product Specific References | PubMed: 11719267 |