neuroglian (Drosophila, neuron-specific) Antibody from DEVELOPMENTAL STUDIES HYBRIDOMA BANK
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| Antigenic Specificity | neuroglian (Drosophila, neuron-specific) |
| Clone | BP 104 anti-Neuroglian |
| Host Species | Mouse |
| Reactive Species | Drosophila |
| Isotype | IgG1 |
| Format | HYBRIDOMA |
| Size | 1 vial cells |
| Concentration | n/a |
| Applications | Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Epitope: Cytoplasmic domain; aa 1236-1302 of isoform B of Uniprot ID P20241. Differential splicing generates a nervous system-specific form of neuroglian. The antibody recognizes a specific form of neuroglian via a cytoplasmic domain generated by alternative splicing. Staining is first seen at about 6 hrs in a subset of neurons, but rapidly expands to include all neurons of the CNS and PNS. It is an exceptionally useful marker for the neurons of the neuron pattern in the PNS and developing eye disc. The PNS staining includes a small number of non-neuronal support cells such as the innermost sheath cell associated with the chordotonal neurons. This antibody works well on Westerns. BP 104 requires detergent permeabilization of tissue to bind to the protein, suggesting that it recognizes an epitope specific to the cytoplasmic domain of this form (isoform B) of the protein [PMID 1693086]. Antibody Registry ID: AB_528402 |
| Immunogen | Membrane protein preparation from cultured embryonic Drosophila neurons., Total protein |
| Other Names | Nrg180; CG1634 |
| Gene, Accession # | Nrg, Gene ID: 31792, UniProt: P20241 |
| Catalog # | BP 104 anti-Neuroglian |
| Price | please inquire |
| Order / More Info | neuroglian (Drosophila, neuron-specific) Antibody from DEVELOPMENTAL STUDIES HYBRIDOMA BANK |
| Product Specific References | PubMed: 1693086 |
DEVELOPMENTAL STUDIES HYBRIDOMA BANK
DEVELOPMENTAL STUDIES HYBRIDOMA BANK
Dr. David Soll
University of Iowa Dept. Biology
Iowa City IA 52242
P: 319-335-3826
F: 319-335-2077
dshb@uiowa.edu
http://dshb.biology.uiowa.edu
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