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Antigenic Specificity | SARS-CoV-2 Spike S1 Protein |
Clone | n/a |
Host Species | n/a |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated, azide-free |
Size | 200 ug |
Concentration | n/a |
Applications | RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Coronaviruses are positive-sense RNA viruses having an extensive range of natural hosts and typically affect the respiratory system. SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2) has four structural proteins, known as the S (spike), E (envelope), M (membrane), and N (nucleocapsid) proteins; the N protein holds the RNA genome, and the S, E, and M proteins together create the viral envelope. The S protein is a large viral transmembrane protein associated in a trimer manner on the virion surface, giving the virion a corona or crown-like appearance. Functionally it is the protein responsible for allowing the virus to attach to and fuse with the membrane of a host cell via the ACE2 protein. The ectodomains in all CoVs S proteins have similar domain organizations, divided into two subunits: the first one, S1, helps in host receptor binding, while the second one, S2, accounts for fusion. It also acts as a critical factor for tissue tropism and the determination of host range. The S protein is one of the proteins of CoVs capable of inducing most important host immune responses. |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | CS1-G200 |
Price | $705 |
Order / More Info | SARS-CoV-2 Spike S1 Protein Antibody from EAGLE BIOSCIENCES INC. |
Product Specific References | n/a |