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Antigenic Specificity | TBLR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 100 µg/ml |
Applications | IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-TBLR1 IHC Antibody, Affinity Purified. TBLR1 is a six WD-40 repeat protein with high sequence homology to TBL1 (transducin beta-like protein 1) and is part of the SMRT (silencing mediator of retinoid and thyroid hormone receptors) and N-CoR (nuclear receptor corepressor) complexes that interact with nuclear receptors and repress transcription. Biochemical characterization of SMRT and N-CoR complexes demonstrate that SMRT and N-CoR are present in complexes that include HDAC3 (histone deacetylase 3), TBL1, and TBLR1. Association with HDAC3 indicates that these complexes may repress transcription through histone deacetylation and chromatin remodeling. |
Immunogen | Epitope: between 100 and 150 |
Other Names | DC42; TBLR1; nuclear receptor corepressor/HDAC3 complex subunit TBLR1; TBL1-related protein 1; Transducin beta-like 1X-related protein 1; MRD41; F-box-like/WD repeat-containing protein TBL1XR1; C21; IRA1; nuclear receptor co-repressor/HDAC3 complex subunit |
Gene, Accession # | Gene ID: 79718, Accession: NP_078941.2, UniProt: Q9BZK7 |
Catalog # | IHC-00031-T |
Price | $121 |
Order / More Info | TBLR1 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |