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Antigenic Specificity | PARD3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse (predicted: rat) |
Isotype | n/a |
Format | affinity purified |
Size | 10 µl |
Concentration | 1000 µg/ml |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-PARD3 antibody, affinity purified. Partitioning defective 3 homolog (Par3) is an adapter protein involved in asymmetrical cell division and cell polarization processes. It seems to play a central role in the formation of epithelial tight junctions and targets the phosphatase PTEN to cell junctions (By similarity). Par3 association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Par3 is required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8TEW0]. |
Immunogen | Between 1306 and C-terminus |
Other Names | PAR3alpha; PAR3-alpha; SE2-5LT1; SE2-5L16; protein phosphatase 1, regulatory subunit 118; PPP1R118; partitioning defective 3 homolog; PARD-3; SE2-5T2; atypical PKC isotype-specific interacting protein; PARD3A; par-3 partitioning defective 3 homolog; ASIP; Atypical PKC isotype-specific-interacting protein; Baz; bazooka; CTCL tumor antigen se2-5; PAR3; PAR-3; par-3 family cell polarity regulator alpha |
Gene, Accession # | Accession: NP_062565.2, Gene ID: 56288, UniProt: Q8TEW0 |
Catalog # | A304-496A-T |
Price | $121 |
Order / More Info | PARD3 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |