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Antigenic Specificity | NCAM-1/CD56 |
Clone | BLR152J |
Host Species | Recombinant Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 10 µl (5+ tests) |
Concentration | 100 µg/ml |
Applications | WB, IHC, ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-NCAM-1/CD56 recombinant monoclonal antibody [BLR152J]. NCAM1, is a cell adhesion protein of the immunoglobulin superfamily that is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. It plays a role in the development of the nervous system by regulating neurogenesis, neurite outgrowth, and cell migration. NCAM1 is also involved in the expansion of T lymphocytes, B lymphocytes and natural killer (NK) cells which play an important role in immune surveillance. One prominent isoform NCAM1, known as cell surface molecule CD56, plays a role in several myeloproliferative disorders such as acute myeloid leukemia and differential expression of this gene is associated with differential disease progression. For example, increased expression of CD56 is correlated with lower survival in acute myeloid leukemia patients. [taken from NCBI Entrez Gene (Gene ID: 4684)]. |
Immunogen | Residues 20-318 (ECD) |
Other Names | N-CAM-1; neural cell adhesion molecule, NCAM; neural cell adhesion molecule 1; NCAM-1; NCAM; MSK39; CD56; antigen recognized by monoclonal antibody 5.1H11; CD antigen CD56 |
Gene, Accession # | Accession: NP_000606.3, Gene ID: 4684, UniProt: P13591 |
Catalog # | A700-152-T |
Price | $127 |
Order / More Info | NCAM-1/CD56 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |