Edit |   |
---|---|
Antigenic Specificity | MSK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted: orangutan) |
Isotype | n/a |
Format | affinity purified |
Size | 100 µl |
Concentration | 200 µg/ml |
Applications | WB, IP, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-MSK1 antibody, affinity purified. MSK1 is a serine/threonine kinase required for the mitogen or stress-induced phosphorylation of the transcription factors CREB (cAMP response element-binding protein) and ATF1 (activating transcription factor-1). MSK1 Directly represses transcription via phosphorylation of 'Ser-1' of histone H2A. MSK1 also phosphorylates 'Ser-10' of histone H3 in response to mitogenics, stress stimuli and epidemal growth-factor (EGF), which results in the transcriptional activation of several immediate early genes, including proto-oncogenes c-fos/FOS and c-jun/JUN. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O75582]. |
Immunogen | Between 752 and C-terminus |
Other Names | 90 kDa ribosomal protein S6 kinase 5; S6K-alpha-5; RSK-like protein kinase; RLPK; RSKL; ribosomal protein S6 kinase alpha-5; nuclear mitogen- and stress-activated protein kinase 1; MSK1; MSPK1; ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
Gene, Accession # | Accession: NP_004746.2, Gene ID: 9252, UniProt: O75582 |
Catalog # | A302-747A |
Price | $433 |
Order / More Info | MSK1 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |