C17orf85 Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | C17orf85 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 100 µl |
| Concentration | 1000 µg/ml |
| Applications | WB, IP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-C17orf85 antibody, affinity purified. C17orf85 (NCBP3) associates with NCBP1/CBP80 to form an alternative cap-binding complex (CBC) which plays a key role in mRNA export. C17orf85 (NCBP3) serves as adapter protein linking the capped RNAs (m7GpppG-capped RNA) to NCBP1/CBP80. Unlike the conventional CBC with NCBP2 which binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus, the alternative CBC with C17orf85 (NCBP3) does not bind snRNA and associates only with mRNA thereby playing a role in only mRNA export. The alternative CBC is particularly important in cellular stress situations such as virus infections and the C17orf85 (NCBP3) activity is critical to inhibit virus growth. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q53F19]. |
| Immunogen | Between 1 and 50 |
| Other Names | CTD-3195I5.5; Protein ELG; nuclear cap-binding protein subunit 3; NCBP3; ELG; CTD-3195I5.1; C17orf85; HSA277841 |
| Gene, Accession # | Accession: XP_005256774.1, Gene ID: 55421, UniProt: Q53F19 |
| Catalog # | A305-865A |
| Price | $433 |
| Order / More Info | C17orf85 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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