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Antigenic Specificity | TIF1 Alpha/TRIM24 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse (predicted: rat, bovine, dog, horse, rabbit, panda, orangutan, monkey, gorilla, chimpan |
Isotype | n/a |
Format | affinity purified |
Size | 100 µl |
Concentration | 100 µg/ml |
Applications | IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-TIF1 Alpha/TRIM24 IHC antibody, affinity purified. TIF1 Alpha/TRIM24 is a member of a family of proteins that control transcription and chromatin remodeling through their interaction with transcription factors. The family of TIF1s (transcriptional intermediary factor 1) includes TIF1-alpha, TIF1-beta, and TIF1-gamma. TIF1-alpha plays an important role in development and mediates transcriptional control by interacting with the AF2 region of nuclear receptors such as estrogen, retinoic acid, and vitamin D3 receptors. TIF1-alpha has been shown to be a repressor of transcription. This transcriptional repression involves histone deacetylation and interaction with members of the heterochromatin protein 1 family. |
Immunogen | Between 700 and 750 |
Other Names | TF1A; TIF1; Tripartite motif-containing protein 24; transcriptional intermediary factor 1; transcription intermediary factor 1-alpha; TIF1-alpha; TIF1ALPHA; E3 ubiquitin-protein ligase TRIM24; RNF82; RING-type E3 ubiquitin transferase TIF1-alpha; RING finger protein 82; PTC6; hTIF1; TIF1A |
Gene, Accession # | Accession: NP_003843.3, Gene ID: 8805, UniProt: O15164 |
Catalog # | IHC-00144 |
Price | $459 |
Order / More Info | TIF1 Alpha/TRIM24 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |