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Antigenic Specificity | CD16 |
Clone | monoclonal |
Host Species | Recombinant Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | WB, IHC, ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-CD16 Recombinant Monoclonal Antibody [BLR163J]. CD16A (FCGR3A) is a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other responses, including antibody dependent cellular mediated cytotoxicity and antibody dependent enhancement of virus infections. CD16A is highly similar to another nearby gene (CD16B, FCGR3B) located on chromosome 1. CD16A is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas CD16B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. [taken from NCBI Entrez Gene (Gene ID: 2214)]. |
Immunogen | Epitope: residues 21-201 (ECD) |
Other Names | neutrophil-specific antigen NA; FCGRIII; FCR-10; FCRIII; FCRIIIA; IGFR3; igG Fc receptor III-2; low affinity immunoglobulin gamma receptor III-a Fc fragment; immunoglobulin G Fc receptor III; low affinity immunoglobulin gamma Fc region receptor III-A; CD16; FCGR3; IMD20; CD16A; CD16a antigen; CD antigen CD16a; FcgammaRIIIA; Fc fragment of IgG, low affinity III, receptor for (CD16); Fc fragment of IgG, low affinity IIIa, receptor (CD16a); Fc gamma receptor III-A; FCG3; Fc-gamma receptor III-2 (CD 16); Fc-gamma receptor IIIb (CD16); Fc-gamma RIII; Fc-gamma RIIIa; Fc-gamma RIII-alpha; fc-gamma RIII-beta; low affinity immunoglobulin gamma Fc region receptor III-B; igG Fc receptor III-1; FCRIIIb; FCRIII; FCR-10; FCGR3A; FCGR3; FCG3; CD antigen CD16b; Fc-gamma receptor IIIb (CD 16); Fc-gamma RIII; Fc gamma receptor IIIb; Fc fragment of IgG, low affinity IIIb, receptor (CD16b); CD16b; CD16A; CD16; fc-gamma RIIIb |
Gene, Accession # | Gene ID: 2214, 2215, Accession: NP_000560.7, UniProt: P08637, O75015 |
Catalog # | A700-163CF |
Price | $794 |
Order / More Info | CD16 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |