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Antigenic Specificity | TAFII68 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-TAFII68 antibody, affinity purified. The TFIID complex is important for coordinating the pre-initiation complex and transcription by RNA Pol II. The complex contains the TFIID protein, TATA binding protein (TBP) and multiple TBP-associated factors (TAFs). TAFII68 was identified as a subunit of the TFIID complex, but has also been found to be associated with the Pol II multiprotein complex. TAFII68 is part of the TET family of proteins that can bind RNA and single-stranded DNA. This family also includes the human sarcoma-associated proteins EWS and TLS. The association of this family of proteins with Pol II suggests that they may bridge the processes of transcription initiation and elongation. The N-terminus domain of TAFII68 in gene fusions has been shown to have oncogenic properties, similar to the chromosomal translocation associated with the EWS gene. |
Immunogen | Between 175 and 225 |
Other Names | TAF2N; TBP-associated factor 15; TATA-binding protein-associated factor 2N; TATA box-binding protein-associated factor 2N (RNA-binding protein 56); TAFII68; TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa; 68 kDa TATA-binding protein-associated factor; RNA-binding protein 56; RBP56/CSMF fusion; RBP56; Npl3; TAF(II)68; TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD (RNA-binding protein 56) |
Gene, Accession # | Accession: NP_631961.1, Gene ID: 8148, UniProt: Q92804 |
Catalog # | A300-307A |
Price | $433 |
Order / More Info | TAFII68 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |