Edit |   |
---|---|
Antigenic Specificity | OSR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 10 µl |
Concentration | 1000 µg/ml |
Applications | IP, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-OSR1 antibody, affinity purified. Oxidative stress responsive 1 (OSR1) is a STE20-related kinase involved in ion transport and fluid and ion homeostasis. OSR1 interacts with SPAK (STE20/SPS1-reated proline/alanine-rich kinase) and together are activated by the upstream kinase WNK1 [with no K (lysine) protein kinase-1]. Activation of OSR1 and SPAK by WNK1 results in the phosphorylation and activation of NKCC1 (Na+-K+-2Cl- co-transporter 1) for the control of cell volume and blood pressure. |
Immunogen | Between 300 and 350 |
Other Names | OSR1; oxidative stress-responsive 1 protein; serine/threonine-protein kinase OSR1 |
Gene, Accession # | Accession: NP_005100.1, Gene ID: 9943, UniProt: O95747 |
Catalog # | A301-578A-T |
Price | $121 |
Order / More Info | OSR1 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |