Edit |   |
---|---|
Antigenic Specificity | ERK1/2, Phospho (T202/Y204, T185/Y187) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted: mouse, rat, D. melanogaster, X. laevis, bovine) |
Isotype | n/a |
Format | affinity purified |
Size | 10 µl |
Concentration | 1000 µg/ml |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-Phospho ERK1/2 (T202/Y204, T185/Y187) antibody, affinity purified. Extracellular signal-regulated kinase 1 (ERK1/p44), also known as mitogen-activated protein kinase 3 (MAPK3), and extracellular signal-regulated kinase 2 (ERK2/p42), also known as mitogen-activated protein kinase 1 (MAPK1), are part of a signal transduction pathway that begins with the small GTPase Ras and continues through a cascade of protein kinases that include Raf and MEK. Activation of this signaling pathway influences many cellular processes such as proliferation, differentiation and survival. ERK1 is very similar in sequence to ERK2/p42 and the activities of both ERK1 and ERK2 are usually considered together as total ERK activity. More recent evidence has shown that ERK1 and ERK2 are not functionally redundant and may have very different and specific roles. |
Immunogen | Surrounding threonine 185 and tyrosine 187 |
Other Names | PRKM1; p38; p40; p41; p41mapk; P42MAPK; ERK2; PRKM2; protein tyrosine kinase ERK2; mitogen-activated protein kinase 2; p42-MAPK; ERT1; ERK; ERK-2; extracellular signal-regulated kinase 2; MAP kinase 1; MAP kinase 2; MAP kinase isoform p42; MAPK 1; MAPK 2; MAPK2; mitogen-activated protein kinase 1; HS44KDAP; MAPK 1; p44-MAPK; P44MAPK; p44-ERK1; P44ERK1; mitogen-activated protein kinase 3; microtubule-associated protein 2 kinase; MAPK 3; MAP kinase isoform p44; MAP kinase 3; HUMKER1A; PRKM3; extracellular signal-related kinase 1; extracellular signal-regulated kinase 1; ERT2; ERK-1; ERK1; insulin-stimulated MAP2 kinase |
Gene, Accession # | Accession: NP_002736.3, Gene ID: 5594, 5595, UniProt: P27361, P28482, P27361, P28482 |
Catalog # | A303-608A-T |
Price | $121 |
Order / More Info | ERK1/2, Phospho (T202/Y204, T185/Y187) Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |